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Table 2 Fold change in gene expression comparing CsA treated B76 cells with or without 10 ng/ml IT

From: The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells

Cancer pathway Gene Description Fold change
Cell adhesion PNN Pinin, desmosome-associated protein 2.2
FAT1 Cadherin-related tumor suppressor homolog 2.3
Cell cyclus BRMS1 Breast cancer metastase suppressor, transcriptional repressor 2.0
NF2 Neurofibromin 2.2
Cell cyclus and transcription factor RB1 Retinoblastoma, tumor suppressor, transcriptional repressor 2.2
TP53 Tumor suppressor, transcription factor 2.3
Cell cyclus or cell proliferation NME1 Expressed in Non-Metastatic cells, nucleoside diphosphate kinase 3.2
Cell growth and proliferation SSTR2 Somatostatin receptor 2, ligand somatostatin 14/28 2,1
DENR Density-regulated protein, involved in translation 2.6
KISS1R Receptor for KISS1 2.8
FLT4 Receptor tyrosine kinase, ligand VEGF C/D 3.1
CXCR4 CXC chemokine receptor, ligand SDF-1 3.4
EPHB2 Receptor tyrosine kinase, ligand ephrin-family members 10.3
Invasion MMP10 Matrix metalloproteinase 2.4
MMP9 Matrix metalloproteinase 5.3
Other METAP2 Methionyl aminopeptidase 2.1
CD82 Metastasis suppressor 2.2
CTSK Cathepsin K, cysteine protease 4.2
NME4 Expressed in Non-Metastatic cells, nucleoside diphosphate kinase 7.6
KISS1 Metastasis suppressor 14.6
Transcription factor MYCL1 Myc-related -3.8
SMAD4 SMAD family member, 2.0
NR4A3 Nuclear-receptor subfamily 4 member A3, potential transcriptional activator 20.6
  1. Results from two independent experiments are analysed together.