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Table 1 Associations between PIGR expression and clinicopathological and investigative parameters

From: Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer

Factor

PIGR expression

p-value

 

median (range)

 

Age

  

≤Median

4.00 (0.00–12.00)

0.258

>Median

5.00 (0.00–12.00)

 

Histological subtype

 

Serous

4.00 (0.00–10.50)

0.002

Endometroid

5.25 (2.00–12.00)

 

Mucinous

8.50 (2.00–12.00)

 

Other

7.00 (1.00–12.00)

 

Differentiation grade

  

Low

6.00 (0.00–12.00)

0.001

High

4.00 (0.00–12.00)

 

Clinical stage

  

I

7.00 (2.00–12.00)

0.084

II

5.00 (1.00–12.00)

 

III

4.00 (0.00–12.00)

 

IV

4.00 (0.00–12.00)

 

KRAS status

  

Wild–type

4.25 (0.00–12.00)

0.061

Mutated

6.75 (2.00–12.00)

 

Ki–67

  

0–10%

6.00 (1.00–12.00)

0.003

11–25%

4.00 (0.00–12.00)

 

>25%

5.00 (0.00–12.00)

 

AR

  

Negative

5.00 (0.00–12.00)

0.674

Positive

4.00 (0.00–12.00)

 

ER

  

Negative

6.00 (0.00–12.00)

0.089

Positive

4.00 (0.00–12.00)

 

PR

  

Negative

4.00 (0.00–12.00)

0.009

Positive

6.50 (0.00–12.00)

 
  1. AR = androgen receptor, ER = oestrogen receptor, PR = progesterone receptor. The analysis of PIGR expression is based on multipliers of staining intensity and fraction of tissue stained (cytoplasmic score).