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Table 3 Concentrations of anti-Hsp60 and anti-Hsp65 IgG antibodies in group of women with ovarian cancer depending on stage of clinical disease progression (by FIGO) and in control group

From: Antibodies against Hsp60 and Hsp65 in the sera of women with ovarian cancer

 

Stage of clinical disease progression (by FIGO)

Controls

I

II

III

IV

n = 80

n = 25

n = 31

n = 60

n = 33

Anti-Hsp60 (AU/ml)

126,99a)b)e)

97,15c)e)

91,92

70,87

62,42

(mean ± SD)

± 121,90

± 91,82

± 160,11

± 78,70

± 33,92

  % of positive results

46%f)

27%f)

17%

17%

10%

  (> 90 percentile for control group)

p = 0.0000

p = 0.0213

p = 0.2047

p = 0.2861

Anti-Hsp65 (AU/ml)

190,34a)b)e)

97,80c)e)

89,36d)

44,17

56,35

(mean ± SD)

± 337,27

± 90,59

± 137,58

± 26,07

± 35,58

  % of positive results

46%f)

27%f)

21%

0%f)

10%

  (> 90 percentile for control group)

p = 0.0000

p = 0.0213

p = 0.0594

p = 0.0493

  1. a)p < 0.05 in group of women with I clinical stage compared to group of women with III clinical stage.
  2. b)p < 0.05 in group of women with I clinical stage compared to group of women with IV clinical stage.
  3. c)p < 0.05 in group of women with II clinical stage compared to group of women with IV clinical stage.
  4. d)p < 0.05 in group of women with III clinical stage compared to group of women with IV clinical stage.
  5. e)p < 0.05 in group of women with I and II clinical stage compared to control group.
  6. f)p < 0.05 in group of women with I, II and IV clinical stage compared to control group.