|
Variable
|
Women with PCOS (n_40)
|
Healthy controls (n_43)
|
p
|
|---|
|
Age, years
|
22.97 ± 5.18
|
23.63 ± 4.60
|
>0.05
|
|
BMI, kg/m2
|
24.40 ± 5.82
|
25.44 ± 4.82
|
>0.05
|
|
Waist/hip ratio
|
0.84 ± 0.78
|
0.83 ± 0.73
|
>0.05
|
|
Fasting insulin, μ IU/ml
|
14.92 ± 9.96
|
9.25 ± 7.90
|
<0.01*
|
|
HOMA-IR
|
3.98(1.4-7.9)
|
1.91(0.74-4.84)
|
<0.01*
|
|
Total cholesterol, mg/dl
|
179.63 ± 26.62
|
151.46 ± 26.74
|
<0.01*
|
|
Triglyceride, mg/dl
|
109.75 ± 54.92
|
78.82 ± 32.55
|
<0.01*
|
|
LDL-C, mg/dl
|
99.45 ± 26.60
|
84.72 ± 23.51
|
<0.01*
|
|
FSH, m IU/ml
|
5.39 ± 1.82
|
5.88 ± 1.76
|
>0.05
|
|
LH, m IU/ml
|
5.79 ± 1.94
|
5.76 ± 2.44
|
>0.05
|
|
Estradiol, pg/ml
|
43.44 ± 22.32
|
72.43 ± 38.00
|
<0.01*
|
|
Free testosterone,pg/m
|
2.81 ± 1.02
|
1.44 ± 0.62
|
<0.01*
|
|
17-OHprogesterone,ng/ml
|
1.41 ± 0.55
|
0.90 ± 0.64
|
<0.01*
|
|
DHEAS, μq/dl
|
275.65 ± 115.45
|
195.67 ± 92.75
|
<0.01*
|
|
CIMT, mm
|
0.51 ± 0.052
|
0.42 ± 0.043
|
<0.01*
|
|
Copeptin, pmol/L
|
12.61 ± 3.05
|
9.60 ± 2.80
|
<0.01*
|
- *p <0.05 was accepted as statistically significant.
- BMI body mass index, HOMA-IR homeostasis model assessment insulin resistance index, HDL-C high density lipoprotein cholesterol, LDL-C LOW density lipoprotein cholesterol, hs-CRP high-sensitive C- reactive protein, TSH thyroid stimulating hormone, FSH follicle-stimulating hormone, LH luteinizing hormone, DHEAS dehydroepiandrosterone sulfate, CIMT carotid intima media thickness.
