Copeptin, a surrogate marker for arginine vasopressin, is associated with cardiovascular risk in patients with polycystic ovary syndrome

Table 1 The Clinical and biochemical/ hormonal data in women with polycistic ovary syndrome (PCOS) patients and healthy controls

Variable	Women with PCOS (n_40)	Healthy controls (n_43)	p
Age, years	22.97 ± 5.18	23.63 ± 4.60	>0.05
BMI, kg/m2	24.40 ± 5.82	25.44 ± 4.82	>0.05
Waist/hip ratio	0.84 ± 0.78	0.83 ± 0.73	>0.05
Fasting insulin, μ IU/ml	14.92 ± 9.96	9.25 ± 7.90	<0.01*
HOMA-IR	3.98(1.4-7.9)	1.91(0.74-4.84)	<0.01*
Total cholesterol, mg/dl	179.63 ± 26.62	151.46 ± 26.74	<0.01*
Triglyceride, mg/dl	109.75 ± 54.92	78.82 ± 32.55	<0.01*
LDL-C, mg/dl	99.45 ± 26.60	84.72 ± 23.51	<0.01*
FSH, m IU/ml	5.39 ± 1.82	5.88 ± 1.76	>0.05
LH, m IU/ml	5.79 ± 1.94	5.76 ± 2.44	>0.05
Estradiol, pg/ml	43.44 ± 22.32	72.43 ± 38.00	<0.01*
Free testosterone,pg/m	2.81 ± 1.02	1.44 ± 0.62	<0.01*
17-OHprogesterone,ng/ml	1.41 ± 0.55	0.90 ± 0.64	<0.01*
DHEAS, μq/dl	275.65 ± 115.45	195.67 ± 92.75	<0.01*
CIMT, mm	0.51 ± 0.052	0.42 ± 0.043	<0.01*
Copeptin, pmol/L	12.61 ± 3.05	9.60 ± 2.80	<0.01*

*p <0.05 was accepted as statistically significant.
BMI body mass index, HOMA-IR homeostasis model assessment insulin resistance index, HDL-C high density lipoprotein cholesterol, LDL-C LOW density lipoprotein cholesterol, hs-CRP high-sensitive C- reactive protein, TSH thyroid stimulating hormone, FSH follicle-stimulating hormone, LH luteinizing hormone, DHEAS dehydroepiandrosterone sulfate, CIMT carotid intima media thickness.

ISSN: 1757-2215