Analysis of apoptosis and angiogenesis in the tumors growing intra-abdominally in the athymic nude mice model. Five-micron sections obtained from the liver, bowels and uterus of the athymic nude mice were fixed in formalin and embedded in paraffin then prepared for the immunohistochemical analyses. The combination of Cisplatin and Gemcitabine significantly induced apoptosis (A), inhibited the angiogenic activity (B) and depressed the MIB-1 index (C). Significant differences are indicated by asterisks. **p < 0.01, *p < 0.05.