Table 1 Genotype and allele frequencies of the COMT Val/Met polymorphism in POI patients and a control group
Population studied | n | COMT G/A genotypes | COMT Alleles | Dominant model | p | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
GG (%) | GA (%) | AA (%) | p | G (%) | A (%) | p | OR (95% CI) | GG | GA + AA | |||
POF patients* | 96 | 9 (9.4) | 50 (52.1) | 37 (38.5) | 0.003 | 68 (35.4) | 113 (58.8) | 0.015 | 1.62 (1.10 – 2.39) | 9 | 87 | 0.0008 |
Control group* | 120 | 33 (27.5) | 47 (39.2) | 40 (33.3) | 113 (47.1) | 127 (52.9) | 33 | 87 | ||||