Skip to main content

Table 1 Genotype and allele frequencies of the COMT Val/Met polymorphism in POI patients and a control group

From: COMT polymorphism influences decrease of ovarian follicles and emerges as a predictive factor for premature ovarian insufficiency

Population studied n COMT G/A genotypes COMT Alleles Dominant model p
GG (%) GA (%) AA (%) p G (%) A (%) p OR (95% CI) GG GA + AA
POF patients* 96 9 (9.4) 50 (52.1) 37 (38.5) 0.003 68 (35.4) 113 (58.8) 0.015 1.62 (1.10 – 2.39) 9 87 0.0008
Control group* 120 33 (27.5) 47 (39.2) 40 (33.3)   113 (47.1) 127 (52.9)    33 87  
  1. *Sample groups are in Hardy Weinberg equilibrium.