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Table 1 Patient characteristics

From: Preoperative HE4 and ROMA values do not improve the CA125 diagnostic value for borderline tumors of the ovary (BOT) – a study of the TOC Consortium

Parameter

N

Median

Range

Age (years)

   

Whole collective

167

47

16-87

Benign diseases

104

48

19-86

BOT without InvImp

48

44

16-83

BOT with InvImp

15

55

25-87

Preoperative HE4 (pmol/L)

   

Benign diseases

104

50

20-1410

BOT without InvImp

48

52

29-2135

BOT with InvImp

15

74

35-461

Preoperative CA125 (IU/ml)

   

Benign diseases

104

21

5-334

Non-invasive BOT

48

25

3-725

Invasive BOT

15

63

12-259

Histological type of BOT

N (without InvImp)

N (with InvImp)

N (total)

Serous

29

10

39

Mucinous

18

4

22

Endometrioid

0

1

1

Mixed

1

0

1

Types of benign diseases

N

%

 

Benign ovarian lesions

48

49.92

 

Ovarian thecofibroma

2

2.08

 

Leiomyomata

55

57.2

 
  1. Abbreviations: BOT: borderline ovarian tumors; InvImp: invasive implants; HE4: human epididymis protein 4; CA125: cancer antigen 125.