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Figure 5 | Journal of Ovarian Research

Figure 5

From: Changes in granulosa cells gene expression associated with growth, plateau and atretic phases in medium bovine follicles

Figure 5

Upstream regulator analysis in the contrast G vs P. The regulators in orange are activated and in blue are considered as inhibited. This analysis is based on the genes that are downstream of the regulators and generates P values that were highly significant for the top regulator PTEN. PTEN, Phosphatase and tensin homolog ; HRAS, V-Ha-ras Harvey rat sarcoma viral oncogene homolog; FOXO3, Forkhead box O3; CDKN1A, Cyclin-dependent kinase inhibitor 1A; RB1, Retinoblastoma 1; FOXO1, Forkhead box O1; FOXM1, Forkhead box M1; MYC, V-myc myelocytomatosis viral oncogene homolog; CDKN2A, Cyclin-dependent kinase inhibitor; SP1, Sp1 transcription factor; E2F1-4, E2F transcription factor 1–4; TP53, Tumor protein p53; RBL1, Retinoblastoma-like 1 (p107); ATF4, Activating transcription factor 4.

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