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Figure 6 | Journal of Ovarian Research

Figure 6

From: Changes in granulosa cells gene expression associated with growth, plateau and atretic phases in medium bovine follicles

Figure 6

Upstream regulator analysis in the contrast G vs P. The regulators in orange are activated and in blue are considered as inhibited. This analysis is based on the genes that are downstream of the regulators and generates P values that were highly significant for the top regulator TP53. TP53, Tumor protein p53; CDKN2A, Cyclin-dependent kinase inhibitor; E2F1-2-3-4, E2F transcription factor 1-2-3-4; CDKN1A, Cyclin-dependent kinase inhibitor 1A; YY1, YY1 transcription factor; FOS, FBJ murine osteosarcoma viral oncogene homolog; SP1, Sp1 transcription factor; HIF1A, Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); MYC, V-myc myelocytomatosis viral oncogene homolog; RB1, Retinoblastoma 1; RBL1, Retinoblastoma-like 1 (p107).

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