Figure 2

GNAI2 expression correlates with ovarian cancer tissue type. A. Data derived from GSE6008 normal n = 4, mucinous n = 13, clear cell n = 8, endometrioid n = 37, serous n = 41. Nonparametric normal and clear p < 0.005, normal and mucinous p < 0.03, normal and endometrioid p < 0.02, normal and serous p < 0.05. Expression is presented as HPRT1 normalized ∆∆CT. B. Data derived from GSE14764. Clear cell n = 2, endometrial ovarian n = 7, serous n = 68. Kruskal-Wallis ANOVA p < 0.005. Expression is presented as Affymetrix MAS 5.0 signal intensity C. Data derived from GSE29450. Normal n = 10. Clear Cell n = 10. Nonparametric p < 0.0001. Values reported as RMA signal intensity. D. GNAI2 expression correlates with estrogen sensitivity. Data derived from GDS4066, ER + n = 7, ER- n = 8. Nonparametric p < 0.006. Values reported as RMA signal intensity.