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Table 2 Metabolic parameters in CC responsive and non-responsive patients with polycystic ovary syndrome

From: Brachial-to-ankle pulse wave velocity as an independent prognostic factor for ovulatory response to clomiphene citrate in women with polycystic ovary syndrome

 

CC responders (n = 38)

CC non-responders (n = 24)

P value

No. of patients with dyslipidemia (%)

6 (16)

11 (38)

0.02

Triglycerides (mg/dl)

90.4 ± 44.9

117.1 ± 67.6

0.08

LDL cholesterol (mg/dl)

112.2 ± 44.6

116.0 ± 32.9

0.73

HDL cholesterol (mg/dl)

65.3 ± 13.5

60.1 ± 15.6

0.18

Total cholesterol (mg/dl)

192.0 ± 42.0

197.9 ± 31.6

0.57

No. of patients with IGT or DM (%)

4 (11)

11 (46)

0.004

75-g OGTT

   

Plasma glucose (mg/dl)

   

Fasting

88.9 ± 8.4

89.6 ± 7.5

0.76

60 min

129.0 ± 36.3

159.9 ± 48.4

0.01

120 min

112.1 ± 21.6

129.7 ± 41.9

0.04

AUC glucose (mg × h/dl)

936.9 ± 192.6

1080.9 ± 267.3

0.03

IRI (μU/ml)

   

Fasting

9.6 ± 7.3

13.7 ± 9.7

0.09

60 min

67.1 ± 34.7

117.6 ± 90.0

0.007

120 min

61.2 ± 36.5

110.7 ± 107.5

0.02

AUC IRI (μU × h/ml)

473.3 ± 225.9

799.1 ± 609.1

0.009

HbA1c (%)

5.4 ± 0.4

5.6 ± 0.4

0.12

HOMA-IR

2.3 ± 1.9

3.4 ± 2.9

0.09

QUICKI

0.36 ± 0.04

0.34 ± 0.05

0.16

  1. CC: clomiphene citrate, IGT: impaired glucose tolerance, DM: diabetes mellitus, AUC: area under the curve, IRI: immunoreactive insulin, HbA1c: hemoglobin A1c, HOMA-IR: homeostasis model assessment of insulin resistance, QUICKI: quantitative insulin-sensitivity check index.