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Figure 4 | Journal of Ovarian Research

Figure 4

From: Gene therapy of ovarian cancer using IL-21-secreting human umbilical cord mesenchymal stem cells in nude mice

Figure 4

The expression of β-catenin and cyclin-D1 in tumor tissues. A. Western blotting results show the expression of β-catenin and cyclin-D1 in the tumor tissues; B. Immunohistochemistry also shows the expression of β-catenin and cyclin-D1. It was found that the expression of β-catenin and cyclin-D1 in tumor tissues from the mice treated with hUCMSCs-LV-IL-21 for four weeks was significantly decreased compared with the hUCMSCs group and hUCMSCs-LV-Vec group or markedly decreased compared with the control group. *p < 0.05, **p < 0.01, and ***p < 0.005. ns: no statistical significant.

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