Table 3 Correlations of the SOX7 protein expression with the clinicopathological features of ovarian cancer and COX2/cyclinD1
Characteristic | Total | SOX7 expression | P | |
|---|---|---|---|---|
Over-expression | Low-expression | |||
All cases | 31 | |||
Pathology type | NS | |||
Serous | 26 | 7 | 19 | |
Mucinous | 2 | 0 | 2 | |
Endometrioid | 3 | 1 | 2 | |
FIGO stage | 0.037 | |||
Early (I-II) | 16 | 7 | 9 | |
Advance (III-IV) | 15 | 1 | 14 | |
Pathology grade | NS | |||
Low (1) | 4 | 1 | 3 | |
High (2 + 3) | 27 | 7 | 20 | |
Age (years) | NS | |||
<40 | 0 | 0 | 0 | |
40-60 | 21 | 5 | 16 | |
> 60 | 10 | 3 | 7 | |
Cyclin D1 | rs = –0.583, p < 0.001 | |||
Over-expression | 26 | 8 | 18 | |
Low-expression | 5 | 0 | 5 | |
COX2 | rs = –0.618, p < 0.001 | |||
Over-expression | 27 | 5 | 22 | |
Low-expression | 4 | 3 | 1 | |