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Table 1 Loss of heterozygosity in 15 STR loci of the granulosa cell tumor

From: Molecular pathogenesis in granulosa cell tumor is not only due to somatic FOXL2 mutation

STR Loci

Location

Alleles

Ra

TPOX

2p23-2per

8, 8

ND

D2S1338

2q35-37.1

22, 23

1.63b

D3S1358

3p21.31

15, 16

1.84b

FGA

4q28

22, 23

1.01

D5S818

5q21-31

11, 11

ND

CSF1PO

5q33.3-34

10, 11

1.86b

D7S820

7q11.21-22

10, 12

0.56b

D8S1179

8q24.1-24.2

11, 11

ND

TH01

11p15.5

9, 9

ND

vWA

12p12-pter

14, 18

1.14

D13S317

13q22-31

10, 13

0.94

D16S539

16q24-qter

9, 11

1.11

D18S51

18q21.3

14, 18

1.06

D19S433

19q12-13.1

13, 14

1.81b

D21S11

21q11.2-q21

30, 31.2

2.12b

  1. aR = (area T1/area T2)/(area N1/area N2); bLoss of heterozygosity (LOH) is positive when R≥ 1.25 or ≤0.8 (ie., 20% change).