Figure 4

DEX increases the expression of Bcl-XL and survivin but not Bcl-2. SKOV-3 and HO-8910 cells were treated with PTX (50 nM) for 24 h with or without DEX pre-treatment (0.1 μM). The relative expression levels of Bcl-2, survivin, and Bcl-XL (mRNAs) were determined by semi-quantitative RT-PCR. A. PCR results of Bcl-2, survivin, and Bcl-XL expression. B. Relative expression levels of Bcl-2, survivin, and Bcl-XL. GAPDH was used as an internal control. *: p < 0.01 vs. control; *#: p < 0.01 vs. PTX-treated cells. PTX: paclitaxel; DEX: dexamethasone. GAPDH: glyceraldehyde-3-phosphate dehydrogenase.