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Table 1 Descriptive characteristics of the study participants

From: Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population

 

PCOS group

Control group

P a

Subjects (n)

248

92

 

Age (years)

28.2 ± 5.4

32.4 ± 5.5

< 0.001

Body weight (kg)

62.7 ± 14.8

56.9 ± 10.3

< 0.001

Body height (cm)

159.4 ± 5.3

159.7 ± 5.3

0.681

BMI (kg/m2)

24.7 ± 5.5

22.3 ± 4.0

< 0.001

Waist circumference (cm)

83.9 ± 13.5

82.7 ± 12.2

0.705

Systolic BP (mmHg)

117 ± 15

115 ± 14

0.178

Diastolic BP (mmHg)

70 ± 11

70 ± 11

0.852

Total cholesterol (mg/dL)

181.9 ± 43.0

189.9 ± 35.5

0.285

Triglycerides (mg/dL)

104.3 ± 67.5

91.6 ± 46.0

0.258

HDL-C (mg/dL)

53.8 ± 12.8

58.6 ± 17.4

0.063

LDL-C (mg/dL)

114.4 ± 43.8

115.3 ± 32.2

0.914

Fasting insulin

9.9 ± 10.5

9.3 ± 15.5

0.733

2 hr insulin

54.8 ± 52.0

32.5 ± 26.5

< 0.001

HbA1C (%)

5.5 ± 0.5

5.3 ± 0.3

0.037

AC (mg/dL)

89.4 ± 12.0

87.6 ± 5.3

0.086

PC (mg/dL)

110.4 ± 36.2

99.0 ± 25.9

0.036

HOMA index (mg/L)

2.3 ± 2.6

2.0 ± 3.4

0.542

A/I (AC/ Fasting Insulin)

16.7 ± 11.7

17.9 ± 11.4

0.489

QUICKI index (mg/L)

3.4 ± 0.8

3.5 ± 0.7

0.674

SHBG (nmol/L)

37.8 ± 29.7

59.6 ± 53.8

0.007

17-OHP (ng/mL)

1.8 ± 1.4

2.0 ± 1.3

0.529

Hirsutism score

5.6 ± 3.8

3.2 ± 2.9

0.016

TSH (μU/mL)

2.1 ± 1.3

2 .0 ± 1.0

0.618

LH (mIU/mL)

8.0 ± 5.3

4.3 ± 2.5

< 0.001

FSH (mIU/mL)

5.6 ± 2.0

6.0 ± 2.4

0.212

E2 (pg/mL)

45.8 ± 22.9

43.1 ± 27.5

0.484

Testosterone (ng/mL)

0.55 ± 0.31

0.35 ± 0.19

< 0.001

Free androgen index

5.98 ± 4.61

4.04 ± 4.02

0.043

PRL (ng/mL)

12.5 ± 6.4

13.5 ± 6.3

0.248

  1. aCompared by t test.