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Table 1 Body weight, ovary weight and visceral fat in all groups at the end of treatment

From: SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling

Group

Body weight (g)

Ovary weight (mg)

Ovary/body weight (%)

Viscal fat (g)

NC

40.7 ± 1.7

9.1 ± 0.8

0.022

0.25 ± 0.03

CR

33.5 ± 1.6*

5.9 ± 0.5*

0.018

0.11 ± 0.03*

CHF

56.3 ± 3.4***

18.7 ± 0.3***

0.032**

1.24 ± 0.20***

SRT

38.7 ± 1.9

5.9 ± 1.0*

0.015

0.32 ± 0.10

NAM

38.7 ± 1.5

11.7 ± 1.1

0.031*

0.33 ± 0.07

  1. Data are means ± S.E.M. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the NC group.
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Journal of Ovarian Research

ISSN: 1757-2215

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