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Table 1 Body weight, ovary weight and visceral fat in all groups at the end of treatment

From: SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling

Group Body weight (g) Ovary weight (mg) Ovary/body weight (%) Viscal fat (g)
NC 40.7 ± 1.7 9.1 ± 0.8 0.022 0.25 ± 0.03
CR 33.5 ± 1.6* 5.9 ± 0.5* 0.018 0.11 ± 0.03*
CHF 56.3 ± 3.4*** 18.7 ± 0.3*** 0.032** 1.24 ± 0.20***
SRT 38.7 ± 1.9 5.9 ± 1.0* 0.015 0.32 ± 0.10
NAM 38.7 ± 1.5 11.7 ± 1.1 0.031* 0.33 ± 0.07
  1. Data are means ± S.E.M. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the NC group.
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