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Table 2 Percentage of mice at different stages of the estrous cycle among groups

From: SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling

Age and estrous cycle stage NC (n = 8) CR (n = 8) CHF (n = 8) SRT (n = 6) NAM (n = 6)
% % % % %
2 months      
Regular cycling 100 100 87.5 100 100
Irregular cycling 0 0 12.5 0 0
3 months      
Regular cycling 100 75 87.5 66.7 83.3
Irregular cycling 0 25 12.5 33.3 16.7
4 months      
Regular cycling 100 62.5 0 0 0
Irregular cycling 0 37.5 100 100 100
5 months      
Regular cycling 66.7 12.5 0 0 0
Irregular cycling 33.3 87.5 100 100 100
6 months      
Regular cycling 75 12.5 0 0 0
Irregular cycling 25 87.5 100 100 100
7 months      
Regular cycling 75 37.5 0 0 0
Irregular cycling 25 62.5 100 100 100
8 months      
Regular cycling 75 37.5 0 16.7 0
Irregular cycling 25 62.5 100 83.3 100
  1. Note: The dietary treatment started at the beginning of 8 weeks (2 months) of age and stopped at the end of 32 weeks (8 months) of age. The drug administration started at the 26 weeks of age and lasted for 6 weeks.
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