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Figure 2 | Journal of Ovarian Research

Figure 2

From: A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis

Figure 2

Concentrations of oxidative stress markers in follicular fluids. Twenty-three infertile women with Stage III or IV endometriosis were recruited for this study. Eleven patients received three courses of GnRHa (1.8 mg s.c. every 28 days), followed by a standard controlled ovarian hyperstimulation (COH) for IVF-ET (ultralong group). Twelve patients received a standard COH with mid-luteal phase GnRHa down-regulation (control group). The levels of oxidative stress markers; 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a marker of DNA damage and hexanoyl-lysine adduct (HEL) as a marker of lipid peroxidation, were measured in the follicular fluid obtained at the time of oocyte retrieval. Values are mean ± SD. Statistical analysis was employed with the Mann–Whitney U-test using the Bonferroni correction.

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