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Table 1 Demographic and clinical characteristics of the study groups

From: Interleukin-2 and SOCS-1 proteins involvement in the pathophysiology of severe ovarian hyperstimulation syndrome-a preliminary proof of concept

   OHSS(5) CONTROL(5) P value
Age (years) Mean + SE 32.6 ± 2.3 36.6 ± 5.8 ns
Median (range) 33 (30–36) 38 (27–41)
Parity Mean + SE 0.8 ± 1.3 0.6 ± 0.5 ns
Median (range) 0 (1–3) 1 (0–1)
BMI (Kg/m2) Mean + SE 24.2 ± 5.7 24.5 ± 5.6 ns
Median (range) 24.9 (16.6-32.4) 22.5 (19.7-34.7)
Cause of infertility:     ns
PCO (%)   1(20) 1 (20)
Mechanical (%)   1(20) 0 (0)
Male factor (%)   2(40) 3 (60)
Unexplained (%)   1(20) 1 (20)
Serum estradiol level on day of hCG administration (pmol/L) Mean + SE 9292 ± 2464 4167 ± 2730 <0.02
Median (range) 9336 (6589–11908) 3645 (1153–8575)
Number of oocytes retrieved Mean + SE 15.8 ± 2.3 7.8 ± 3.9 <0.002
Median (range) 16 (12–18) 9 (2–12)
IL-2 mRNA levels Mean + SE 2.449 ± 0.255 1.043 ± 0.146 <0.01
Median (range) 2.272 (1.915-3.403) 1.0 (0.6-1.59)
SOCS-1 mRNA levels Mean + SE 0.541 ± 0.144 1.171 ± 0.423 0.22
Median (range) 0.425 (0.225-0.974) 1.0 (0.285-2.821)