Skip to main content

Table 3 Hazard ratios (95% confidence intervals) for the association between 2-year lagged cumulative updated HEI-2005 and ovarian cancer from 1986 through 2010 among women in the NHS

From: A prospective cohort study of dietary indices and incidence of epithelial ovarian cancer

   HEI-2005
  N cases ≤56 >56-63 >63-68 >68-74 >74 P trend
N cases   127 117 129 162 161  
Person-years   294,749 294,665 294,337 293,738 292,082  
Age-adjusted 696 1.00 (Ref) 0.82 (0.63,1.05) 0.85 (0.66,1.09) 0.99 (0.78,1.26) 0.92 (0.72,1.17) 0.98
Multivariable* 696 1.00 (Ref) 0.79 (0.61,1.03) 0.82 (0.63,1.06) 0.93 (0.72,1.20) 0.85 (0.65,1.12) 0.57
Invasive* 592 1.00 (Ref) 0.80 (0.60,1.05) 0.80 (0.60,1.05) 0.91 (0.69,1.20) 0.86 (0.64,1.15) 0.60
Borderline* 57 1.00 (Ref) 1.00 (0.45,2.24) 1.11 (0.50,2.43) 0.97 (0.42,2.20) 0.54 (0.20,1.43) 0.31
Serous/poorly differentiated* 435 1.00 (Ref) 0.81 (0.59,1.13) 0.91 (0.66,1.25) 0.91 (0.66,1.26) 0.90 (0.64,1.27) 0.79
Non-serous* 148 1.00 (Ref) 0.77 (0.46,1.31) 0.70 (0.41,1.21) 1.03 (0.62,1.69) 0.83 (0.49,1.43) 0.81
Rapidly fatal* 247 1.00 (Ref) 0.76 (0.51,1.14) 0.62 (0.40,0.94) 0.67 (0.44,1.02) 0.75 (0.50,1.13) 0.15
Less aggressive* 274 1.00 (Ref) 0.79 (0.52,1.18) 0.89 (0.60,1.32) 1.08 (0.73,1.59) 0.85 (0.556,1.29) 0.89
  1. *Adjustment factors are listed in the Statistical Analyses section.
  2. P values for heterogeneity by tumor subtype were 0.42, 0.95, and 0.32 for invasive versus borderline, serous/poorly differentiated versus non-serous, and rapidly fatal versus less aggressive tumors, respectively.