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Table 5 Association of the RsaI genotypes and the outcome of COH/IVF in the homogenous rFSH dose group (100 IU per day) in the Recessive model

From: ESR1 and ESR2 gene polymorphisms are associated with human reproduction outcomes in Brazilian women

Variáveis RsaIG/A- rs256049
GG GA + AA U p
N Median Mínimum Maximum N Median Minimum Maximum   
Age (years) 95 32 24 37 10 35 31 37 275,5 0,029**
BMI (kg/m2) 92 24,115 17,71 31,62 9 24,34 16,8 28,71 355,5 0,49
Estradiol (pg/ml) 95 42,11 27,06 346,9 10 49,395 40,3 253,58 292,5 0,046*
Follicles 95 5 0 28 10 5 0 13 423 0,57
Oocytes 89 5 0 28 8 6,5 0 13 338 0,81
Mature oocytes 89 4 0 25 8 4 0 11 343,5 0,87
Embryos 79 3 0 17 7 3 1 5 247 0,64
Good quality embryos 78 2 0 12 7 1 0 3 190,5 0,18
Days of rFSH 82 9 7 14 7 8 7 9 107,5 0,005*
Dose of rFSH (UI) 82 900 700 1400 7 800 700 900 107,5 0,005*
  1. N: Number of Individuals; SD: Standard deviation; *p < 0.05. Mann–Whitney results represented by U.
  2. ** Individuals with the allele A had better results of COH even thought their average age values were higher than individuals with the genotype GG.