SDHB silencing contributed to ovarian cancer cell proliferation in SKOV3 and A2780 cells. (A, B) Cell proliferation was assessed following SDHB silencing treatment for 6 days by CCK8. Mean ± SEM. *P < 0.05, **P < 0.01 and ***P < 0.001. (C) 48 h post transfection, p-ERK, ERK were examined by western blot. (D, E) 48 h post-transfection, SKOV3 and A2780 cells were treated with DDP at indicated concentration for 24 h, cleaved caspase 3, total caspase 3, and Bcl-2 were then analysed by western blot.