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Figure 4 | Journal of Ovarian Research

Figure 4

From: Small-molecule inhibitor of Bcl-2 (TW-37) suppresses growth and enhances cisplatin-induced apoptosis in ovarian cancer cells

Figure 4

Effect of TW-37 on Soft-agar colony formation in OVCAR3, OV-90 and SKOV3 DDP cells. OVCAR3, OV-90 and SKOV3DDP cells treated with 250, 500 and 750 nM of TW-37 for 72 hs were evaluated by the Soft-agar colony assay. The colonies in the soft agar were counted in all untreated and treated wells after 12 days. There was a significant reduction in the colony formation in OVCAR3, OV-90 and SKOV3DDP cells treated with TW-37 compared with control cells ( the control was as 1). The experiments are repeated for three times. P values represent comparisons between cells treated by TW-37 and control using the paired t test. Vs control, * P < 0.05; ** P < 0.01.

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