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Table 4 The array and qPCR results for selected differentially expressed genes

From: Polycystic ovarian syndrome is accompanied by repression of gene signatures associated with biosynthesis and metabolism of steroids, cholesterol and lipids

Gene name Gene symbol Acess. No Array result qPCR result
FC P value FC P value
Chymotrypsinogen b1 CTRB1 NM_012536 20 (↑) 0.00003 27.3 (↑) 0.0023
Myosin, heavy chain 6, cardiac muscle, alpha MYH6 NM_017239 17 (↑) 0.0004 14 0 (↑) 0.06
Plasminogen activator, urokinase PLAU NM_013085 5.37 (↑) 0.0008 5.56 (↑) 0.13
St3 beta-galactoside alpha-2,3-sialyltransferase 6 ST3GAL6 NM_207602 4.9 (↑) 0.0126 5.28 (↑) 0.05
Inhibin beta-a INHBA NM_017128 5.43(↑) 0.002 28.9 (↑) 0.04
Steroidogenic acute regulatory protein STAR NM_031558 14.57 (↓) 0.001 25.5 (↓) 0.0018
Hydroxysteroid (17-beta) dehydrogenase 7 HSD17B7 NM_017235 30.52 (↓) 0.0003 47.67 (↓) 0.006
Oxidative stress induced growth inhibitor 1 OSGIN1 NM_138504 26.98 (↓) 0.000022 21.57 (↓) 0.0047
Relaxin 1 RLN1 NM_013413 133.9 (↓) 0.0014 255.8 (↓) 0.019
  1. FC = Fold change, ↑ and ↓ indicate the activated and repressed genes in DHT treated compared to CTL rat groups, p ≤ 0.05 considered as significant.