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Table 4 The array and qPCR results for selected differentially expressed genes

From: Polycystic ovarian syndrome is accompanied by repression of gene signatures associated with biosynthesis and metabolism of steroids, cholesterol and lipids

Gene name

Gene symbol

Acess. No

Array result

qPCR result

FC

P value

FC

P value

Chymotrypsinogen b1

CTRB1

NM_012536

20 (↑)

0.00003

27.3 (↑)

0.0023

Myosin, heavy chain 6, cardiac muscle, alpha

MYH6

NM_017239

17 (↑)

0.0004

14 0 (↑)

0.06

Plasminogen activator, urokinase

PLAU

NM_013085

5.37 (↑)

0.0008

5.56 (↑)

0.13

St3 beta-galactoside alpha-2,3-sialyltransferase 6

ST3GAL6

NM_207602

4.9 (↑)

0.0126

5.28 (↑)

0.05

Inhibin beta-a

INHBA

NM_017128

5.43(↑)

0.002

28.9 (↑)

0.04

Steroidogenic acute regulatory protein

STAR

NM_031558

14.57 (↓)

0.001

25.5 (↓)

0.0018

Hydroxysteroid (17-beta) dehydrogenase 7

HSD17B7

NM_017235

30.52 (↓)

0.0003

47.67 (↓)

0.006

Oxidative stress induced growth inhibitor 1

OSGIN1

NM_138504

26.98 (↓)

0.000022

21.57 (↓)

0.0047

Relaxin 1

RLN1

NM_013413

133.9 (↓)

0.0014

255.8 (↓)

0.019

  1. FC = Fold change, ↑ and ↓ indicate the activated and repressed genes in DHT treated compared to CTL rat groups, p ≤ 0.05 considered as significant.