Figure 1

Evaluation of cellular responses of human ovarian cancer CAOV-3 and OVCAR-3 cells to 120 μM resveratrol treatment. A. (a) MTT cell proliferation assay performed on the two cell lines cultured normally (N) and incubated in 0.02% DMSO containing medium without (DMSO) or with 100 μM and 120 μM resveratrol supplementation (Res) for 48 hours. *, compared with N group, P < 0.05, (b) Viable cell counting of 120 μM resveratrol-treated CAOV-3 and OVCAR-3 cells at 24 h, 48 h and 72 h points. *, P < 0.05 in comparison with data collected at 24 h point. B. Hematoxylin and eosin morphological staining (H/E) and TUNEL apoptotic cell assay. C. Flow cytometry determination of cell cycle distribution and apoptosis in CAOV-3 and OVCAR-3 cells after 120 μM resveratrol treatment for 48 hours.