Expression of Lysine-specific demethylase 1 in human epithelial ovarian cancer

Table 1 Expression of LSD1 in different ovarian epithelial lesions and normal ovarian epithelia

Clinicopathological features		Cases (N)	LSD1				Positive (%)	P
Clinicopathological features		Cases (N)	—	+	++	+++	Positive (%)	P
Normal ovarian epithelia		50	25	20	5	0	50	0.000^ab
Serous epithelial lesions	Serous cystadenoma	53	15	25	10	3	72	0.010^c
	Borderline serous cystadenoma	50	9	10	25	6	82	0.000^d
	Borderline serous cystadenoma	50	9	10	25	6	82	0.002ⁱ
	Serous cystadenocarcinoma	96	6	9	31	50	94	0.000^ejk
Mucinous epithelial lesions	Mucinous cystadenoma	59	16	25	16	2	73	0.003^f
	Borderline mucinous cystadenoma	63	11	17	29	6	83	0.000^g
	Borderline mucinous cystadenoma	63	11	17	29	6	83	0.009^l
	Mucinous cystadenocarcinoma	36	3	5	9	19	92	0.000^hmn

^aNon-parametric Jonckheere-Terpstra test, P value of normal and serous groups.
^bNon-parametric Jonckheere-Terpstra test, P value of normal and mucinous groups.
^cnormal ovarian epithelia versus serous cystadenoma; Z = −2.587, P = 0.010.
^dnormal ovarian epithelia versus borderline serous cystadenoma; Z = −5.068, P = 0.000.
^enormal ovarian epithelia versus serous cystadenocarcinoma; Z = −8.404, P = 0.000.
^fnormal ovarian epithelia versus mucinous cystadenoma; Z = −3.000, P = 0.003.
^gnormal ovarian epithelia versus borderline mucinous cystadenoma; Z = −5.073, P = 0.000.
^hnormal ovarian epithelia versus mucinous cystadenocarcinoma; Z = −6.277, P = 0.000.
ⁱserous cystadenoma versus borderline serous cystadenoma; Z = −3.126, P = 0.002.
^jserous cystadenoma versus serous cystadenocarcinoma; Z = −7.106, P = 0.000.
^kborderline serous cystadenoma versus serous cystadenocarcinoma; Z = −4.735, P = 0.000.
^lmucinous cystadenoma versus borderline mucinous cystadenoma; Z = −2.611, P = 0.009.
^mmucinous cystadenoma versus mucinous cystadenocarcinoma; Z = −5.146, P = 0.000.
ⁿborderline mucinous cystadenoma versus mucinous cystadenocarcinoma; Z = −3.824, P = 0.000.
Z= Z-score.

ISSN: 1757-2215