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Table 1 Single and coordinate pattern of Rb1, P16 and ER expression in ovarian epithelial carcinoma cases studied (n = 130)

From: Comparative analysis of Rb1, P16 and ER as diagnostic, prognostic and potential targets for therapeutic agents in ovarian epithelial tumors: an immunohistochemical study of 130 ovarian carcinomas

Tumor type

Rb1+

P16+

ER-

Rb1+/ P16+

Rb1+/ P16-

Rb1+/ ER+

P16+/ ER+

Rb1+/ P16+/ ER+

Rb1-/ P16-/ ER-

High grade serous [HGSC] (n = 67)

36 (54 %)

45 (67 %)

30 (45 %)

20 (30 %)

16 (24 %)

13 (19 %)

21 (31 %)

7 (10 %)

3 (4 %)

Low grade serous [LGSC] (n = 10)

7 (70 %)

3 (30 %)

7 (70 %)

2 (20 %)

5 (50 %)

5 (50 %)

2 (20 %)

1 (10 %)

1 (10 %)

Endometrioid (EC) (n = 34)

16 (47 %)

21 (62 %)

17 (50 %)

7 (21 %)

9 (26 %)

2 (6 %)

12 (35 %)

2 (6 %)

2 (6 %)

Mucinous carcinoma (MC) (n = 19)

11 (58 %)

2 (11 %)

3 (16 %)

1 (5 %)

10 (52 %)

1 (5 %)

1 (5 %)

0

6 (32 %)

Total (n = 130)

70 (54 %)

71 (55 %)

57 (44 %)

30 (23 %)

40 (31 %)

17 (13 %)

36 (28 %)

10 (8 %)

12 (9 %)