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Table 5 Significantly enriched GO terms in the largest component of I ∃0.8

From: Integrative network analysis for survival-associated gene-gene interactions across multiple genomic profiles in ovarian cancer

Category

ID

Description

p-value

Adjusted p-value (FDR)

Count

Total

MF

GO:0044822

poly(A) RNA binding

4.37E-12

1.35E-09

50

1180

CC

GO:0005654

nucleoplasm

1.93E-09

6.54E-08

63

1745

CC

GO:0070062

extracellular vesicular exosome

2.39E-09

7.09E-08

59

1589

BP

GO:0006915

apoptotic process

1.32E-07

1.20E-05

49

1305

BP

GO:0016567

protein ubiquitination

1.75E-07

1.52E-05

28

542

CC

GO:0005730

nucleolus

5.61E-06

1.06E-04

38

1072

CC

GO:0031226

intrinsic component of plasma membrane

1.66E-05

2.89E-04

49

1612

BP

GO:0006366

transcription from RNA polymerase II promoter

1.60E-05

6.57E-04

26

611

CC

GO:0005887

integral component of plasma membrane

5.07E-05

8.34E-04

46

1546

BP

GO:0071156

regulation of cell cycle arrest

2.62E-05

9.70E-04

10

116

BP

GO:0001775

cell activation

5.63E-05

1.86E-03

31

856

BP

GO:0045087

innate immune response

7.46E-05

2.34E-03

34

993

CC

GO:0000228

nuclear chromosome

1.60E-04

2.43E-03

19

453

MF

GO:0042803

protein homodimerization activity

4.87E-05

3.26E-03

26

781

MF

GO:0019901

protein kinase binding

4.93E-05

3.26E-03

22

603

MF

GO:0008201

heparin binding

5.51E-05

3.40E-03

11

182

BP

GO:0071901

negative regulation of protein serine/threonine kinase activity

1.29E-04

3.69E-03

10

140

BP

GO:0007596

blood coagulation

1.36E-04

3.80E-03

22

541

CC

GO:0005783

endoplasmic reticulum

3.16E-04

4.27E-03

51

1918

BP

GO:0051222

positive regulation of protein transport

1.88E-04

4.88E-03

15

301

BP

GO:0000086

G2/M transition of mitotic cell cycle

2.27E-04

5.70E-03

10

150