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Table 1 Schematic list of major procedures for treatment of infertility

From: Perspective in infertility: the ovarian stem cells

  Indication Success rate Advantages Disadvantages
IUI - Unexplained infertility variable: ~15-20 % - Very simple procedure Virtually no disadvantages
Factors reducing the success rate:
- High concentration of motile sperms
- Older age of the woman
- Mild/moderate male infertility
- Poor egg quality
- Poor sperm quality
- Cervical factor infertility - Severe endometriosis
- Severe damage to fallopian tubes
- Blockage of fallopian tubes
- Minimal endometriosis
IVF - Unexplained infertility ~30 % of all treatment cycles (depending on the age of the woman) - Treatment of choice with donor eggs - Multiple pregnancies
- Low sperm numbers or motility
- Reduce surgery on damages tubes
- Infrequent or absent ovulation
- Tubal factor infertility
- Cervical factor infertility
- Immunological factor infertility
- Ectopic pregnancy
- Moderate or severe endometriosis - Painful treatment
- Expensive treatment
- Age-related infertility
- Failure of other fertility treatments
ICSI - Low numbers of motile sperm variable: ~8.5 % to 33.5 % (age range between 35 and 44) - Overcomes male infertility - Higher risk of miscarriage
- Abnormal morphology sperm
- Efficient where few eggs are available
- High levels of antisperm antibodies
- Success depends on different factors (age of female, quality of eggs, sperm, uterus)
- Prior or repeated fertilization failure
- Limited frozen sperm
- Obstruction of the male tract sperm
- Painful treatment
- Expensive treatment
  1. IUI Intrauterine insemination, IVF In vitro fertilization, ICSI Intracyplasmatic sperm injection