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Table 3 The percentage of AR and ER positive cells in ovaries in CR and fed ad libitum mice. Data expressed as mean ± SD

From: Caloric restriction increases ratio of estrogen to androgen receptors expression in murine ovaries - potential therapeutic implications

Group Control Experimental
AR ER AR ER
Ovarian surface epithelium Lack of reaction (−) 9,2 ± 13,0 22,5 ± 4,2 10,3 ± 12,2 6,5* ± 8,5
Weak reaction (+) 28,3 ± 11,7 52,9 ± 6,8 15,7* ± 13,4 15,1* ± 6,3
Strong reaction (++) 62,0 ± 15,6 22,1 ± 7,1 56,3 ± 15,3 6,9* ± 3,5
Very strong reaction (+++) 0,6 ± 1,8 2,5 ± 2,2 17,7* ± 6,6 71,5* ± 12,6
Granulosa cells Lack of reaction (−) 10,0 ± 11,9 0,2 ± 0,7 13,6 ± 7,5 0,1 ± 0,4
Weak reaction (+) 6,4 ± 3,1 9,5 ± 9,0 14,2* ± 5,9 2,3* ± 3,0
Strong reaction (++) 26,5 ± 8,9 72,7 ± 10,4 25,9 ± 7,7 18,7* ± 6,0
Very strong reaction (+++) 57,1 ± 10,9 17,6 ± 9,5 46,3* ± 6,2 79,0* ± 6,5
Theca cells Lack of reaction (−) 89,4 ± 6,4 79,1 ± 6,8 34,8* ± 6,1 28,7* ± 10,7
Weak reaction (+) 9,0 ± 4,9 11,3 ± 4,2 49,7* ± 6,5 50,2* ± 9,9
Strong reaction (++) 0,5 ± 1,4 7,9 ± 4,6 11,1* ± 4,3 13,3 ± 6,0
Very strong reaction (+++) 1,0 ± 3,2 1,6 ± 2,6 4,2* ± 4,9 7,7* ± 4,5
Luteal cells Lack of reaction (−) 24,9 ± 7,8 76,8 ± 15,2 93,1* ± 1,9 33,8* ± 7,8
Weak reaction (+) 73,7 ± 6,9 14,3 ± 7,3 6,9* ± 2,0 50,6* ± 5,5
Strong reaction (++) 1,3 ± 0,8 8,3 ± 8,1 0,1* ± 0,2 14,1 ± 5,0
Very strong reaction (+++) 0,1 ± 0,2 0,6 ± 0,8 0,1 ± 0,2 1,5 ± 1,6
Endothelial cells Lack of reaction (−) 20,6 ± 9,6 20,8 ± 9,7 0,1* ± 0,2 17,7 ± 7,8
Weak reaction (+) 70,4 ± 10,6 50,9 ± 7,7 21,0* ± 12,6 15,5* ± 8,4
Strong reaction (++) 8,1 ± 4,8 25,9 ± 11,7 52,6* ± 5,2 47,1* ± 7,7
Very strong reaction (+++) 0,8 ± 1,8 2,4 ± 3,2 26,3* ± 9,2 19,7* ± 12,9
Interstitial cells Lack of reaction (−) 5,5 ± 8,3 24,0 ± 5,0 19,1* ± 11,3 6,3* ± 4,4
Weak reaction (+) 72,4 ± 7,6 47,6 ± 5,8 79,4 ± 10,7 21,7* ± 10,3
Strong reaction (++) 20,2 ± 11,6 22,8 ± 5,9 1,4* ± 1,5 56,8* ± 6,3
Very strong reaction (+++) 1,8 ± 2,2 5,7 ± 3,9 0,1 ± 0,3 15,3* ± 9,7
  1. *p < 0,05 vs control