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Table 3 The percentage of AR and ER positive cells in ovaries in CR and fed ad libitum mice. Data expressed as mean ± SD

From: Caloric restriction increases ratio of estrogen to androgen receptors expression in murine ovaries - potential therapeutic implications

Group

Control

Experimental

AR

ER

AR

ER

Ovarian surface epithelium

Lack of reaction (−)

9,2 ± 13,0

22,5 ± 4,2

10,3 ± 12,2

6,5* ± 8,5

Weak reaction (+)

28,3 ± 11,7

52,9 ± 6,8

15,7* ± 13,4

15,1* ± 6,3

Strong reaction (++)

62,0 ± 15,6

22,1 ± 7,1

56,3 ± 15,3

6,9* ± 3,5

Very strong reaction (+++)

0,6 ± 1,8

2,5 ± 2,2

17,7* ± 6,6

71,5* ± 12,6

Granulosa cells

Lack of reaction (−)

10,0 ± 11,9

0,2 ± 0,7

13,6 ± 7,5

0,1 ± 0,4

Weak reaction (+)

6,4 ± 3,1

9,5 ± 9,0

14,2* ± 5,9

2,3* ± 3,0

Strong reaction (++)

26,5 ± 8,9

72,7 ± 10,4

25,9 ± 7,7

18,7* ± 6,0

Very strong reaction (+++)

57,1 ± 10,9

17,6 ± 9,5

46,3* ± 6,2

79,0* ± 6,5

Theca cells

Lack of reaction (−)

89,4 ± 6,4

79,1 ± 6,8

34,8* ± 6,1

28,7* ± 10,7

Weak reaction (+)

9,0 ± 4,9

11,3 ± 4,2

49,7* ± 6,5

50,2* ± 9,9

Strong reaction (++)

0,5 ± 1,4

7,9 ± 4,6

11,1* ± 4,3

13,3 ± 6,0

Very strong reaction (+++)

1,0 ± 3,2

1,6 ± 2,6

4,2* ± 4,9

7,7* ± 4,5

Luteal cells

Lack of reaction (−)

24,9 ± 7,8

76,8 ± 15,2

93,1* ± 1,9

33,8* ± 7,8

Weak reaction (+)

73,7 ± 6,9

14,3 ± 7,3

6,9* ± 2,0

50,6* ± 5,5

Strong reaction (++)

1,3 ± 0,8

8,3 ± 8,1

0,1* ± 0,2

14,1 ± 5,0

Very strong reaction (+++)

0,1 ± 0,2

0,6 ± 0,8

0,1 ± 0,2

1,5 ± 1,6

Endothelial cells

Lack of reaction (−)

20,6 ± 9,6

20,8 ± 9,7

0,1* ± 0,2

17,7 ± 7,8

Weak reaction (+)

70,4 ± 10,6

50,9 ± 7,7

21,0* ± 12,6

15,5* ± 8,4

Strong reaction (++)

8,1 ± 4,8

25,9 ± 11,7

52,6* ± 5,2

47,1* ± 7,7

Very strong reaction (+++)

0,8 ± 1,8

2,4 ± 3,2

26,3* ± 9,2

19,7* ± 12,9

Interstitial cells

Lack of reaction (−)

5,5 ± 8,3

24,0 ± 5,0

19,1* ± 11,3

6,3* ± 4,4

Weak reaction (+)

72,4 ± 7,6

47,6 ± 5,8

79,4 ± 10,7

21,7* ± 10,3

Strong reaction (++)

20,2 ± 11,6

22,8 ± 5,9

1,4* ± 1,5

56,8* ± 6,3

Very strong reaction (+++)

1,8 ± 2,2

5,7 ± 3,9

0,1 ± 0,3

15,3* ± 9,7

  1. *p < 0,05 vs control