Table 3 MicroRNAs significantly down-regulated in metastatic serous ovarian cancer compared to normal ovarian tissues
miRID | Adjusted p-value (Kruskal-Wallis) | Adjusted p-value (LIMMA) | log2 fold change | Chromosomal location | Cytogenetic band |
|---|---|---|---|---|---|
Down-regulated | |||||
  hsa-let-7a | 1.18E-05 | 8.84E-08 | −1.029 | 9: 94175957-94176036 [+] | 9q22.32 |
  hsa-miR-29a | 0.000115739 | 1.75E-05 | −1.032 | 7: 130876747-130876810 [-] | 7q32.3 |
  hsa-miR-126 | 9.83E-06 | 1.70E-06 | −1.107 | 9: 136670602-136670686 [+] | 9q34.3 |
  hsa-miR-29c | 0.000265228 | 9.82E-05 | −1.148 | 1: 207801852-207801939 [-] | 1q32.2 |
  hsa-miR-132 | 0.001852309 | 0.000402718 | −1.162 | 17: 2049908-2050008 [-] | 17p13.3 |
  hsa-miR-101 | 5.45E-05 | 1.42E-05 | −1.352 | 1: 65058434-65058508 [-] | 1p31.3 |
  hsa-miR-26a | 2.74E-07 | 1.71E-09 | −1.373 | 3: 37969404-37969480 [+] | 3p22.2 |
  hsa-let-7b | 8.28E-07 | 2.42E-09 | −1.509 | 22: 46113686-46113768 [+] | 22q13.31 |
  hsa-miR-143 | 2.06E-06 | 1.58E-09 | −1.953 | 5: 149428918-149429023 [+] | 5q32 |
  hsa-miR-9 | 0.000532847 | 0.000152253 | −1.955 | 1: 156420341-156420429 [-] | 1q22 |
  hsa-let-7c | 2.21E-06 | 1.72E-08 | −1.966 | 21: 16539828-16539911 [+] | 21q21.1 |
  hsa-miR-214 | 2.06E-06 | 2.30E-08 | −2.233 | 1: 172138798-172138907 [-] | 1q24.3 |
  hsa-miR-100 | 2.63E-07 | 2.73E-10 | −2.369 | 11: 122152229-122152308 [-] | 11q24.1 |
  hsa-miR-125b | 2.87E-07 | 4.47E-11 | −2.488 | 11: 122099757-122099844 [-] | 11q24.1 |
  hsa-miR-202 | 6.46E-05 | 4.59E-05 | −2.533 | 10: 133247511-133247620 [-] | 10q26.3 |
  hsa-miR-99a | 1.91E-07 | 4.00E-12 | −2.821 | 21: 16539089-16539169 [+] | 21q21.1 |
  hsa-miR-195 | 1.91E-07 | 1.46E-13 | −2.945 | 17: 7017615-7017701 [-] | 17p13.1 |
  hsa-miR-145 | 7.96E-07 | 6.22E-10 | −3.137 | 5: 149430646-149430733 [+] | 5q32 |
  hsa-miR-1 | 2.06E-06 | 2.04E-10 | −3.426 | 20: 62554306-62554376 [+] | 20q13.33 |
  hsa-miR-133a | 4.12E-05 | 4.92E-07 | −3.705 | 18: 21825698-21825785 [-] | 20q13.33 |