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Table 1 Comparison between cisplatin and cisplatin@CB[7] toxicty by MTT assay. The in vitro cytotoxicity of cisplatin and cisplatin@CB[7] in the human ovarian cancer cell line A2780 and its cisplatin-resistant cell line A2780-Rab25. IC50 is defined as the concentration of drug required to inhibition of cell growth by 50 % ovarian cancer cell line A2780 and its cisplatin-resistant cell line A2780-Rab25. IC50 is defined as the concentration of drug required to inhibition of cell growth by 50 %

From: Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model

Cell line IC50 (μM) Cisplatin Cisplatin@CB[7]
A2780 0.16 ± 0.01 0.16 ± 0.001
A2780-Rab25 0.47 ± 0.04 0.42 ± 0.02