Fig. 8

Immunohistochemical localization of aromatase cytochrome P450. Aromatase expression progresses along with follicle development. No or weak aromatase protein was detected in 150–300 μm early-small antral follicles (left). Positive staining was evident in >300 large antral follicles and more concentrated inside the cytoplasm of mural cells, lying on the basal membrane (central). Control sections did not exhibit any positive staining (right). Scale bar = 50 μm