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Table 2 HE4 reference range in healthy populations according to age or menopause status

From: Determination of reference intervals of serum levels of human epididymis protein 4 (HE4) in Chinese women

  Number Value (mean ± SD) Reference range (2.5–97.5 %)
Ages*    
<40 201 45.85 ± 10.72 29.25–68.50
40–49 102 47.80 ± 9.73 32.11–68.96
50–59 104 54,11 ± 14.30 33.04–88.67
60–69 108 59.91 ± 14.33 34.72–92.35
≥70 103 77.57 ± 23.20 45.18–132.00
Pre-menopause 308 46.61 ± 10.70 29.25–68.96
Post-menopause 310 63.94 ± 20.21 34.72–114.90
Overall 618 55.30 ± 18.35 31.82–105.10
  1. *A statistical significant difference in HE4 was found between each age group (p < 0.0001) except between <40 and 40–49