Table 3 Influences of age, menopause or malignancy on HE levels
| Parameter | Number | HE4 Value | P |
|---|---|---|---|
| Median (range) | |||
| Age | <0.001 | ||
| <40 | 628 | 47.275 (15–2982) | |
| 40–49 | 544 | 51.01 (24.07–4322) | |
| 50–59 | 520 | 59.47 (26.08–5234) | |
| 60–69 | 371 | 66.63 (23.3–3844) | |
| ≥70 | 268 | 84.33 (24.22–2276) | |
| Menopause | <0.001 | ||
| Pre-menopause | 1206 | 48.81 (15–4322) | |
| Post-menopause | 1125 | 68.46 (23.3–5234) | |
| Malignancy status | <0.001 | ||
| Healthy | 618 | 51.09 (23.3–166) | |
| Benign | 765 | 51.92 (15–5234) | |
| Malignant | 948 | 67.935 (26.08–4603) | |
| Overall | 2331 | 56.51 (15–5234) |