Fig. 2From: Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced ratsLight micrographs of nuclear maturation of oocytes cultured for, (a) 48 h in the presence of metformin at germinal vesicle breakdown (arrow) from the control; (b) 12 h in the presence of metformin at meiosis I (arrow) from the PCOS-induced rats. Aceto-orcein staining (1000×)Back to article page