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Table 2 Expansion of cumulus cells of rat cumulus oocyte complexes in control, sham, and PCOS groups in the absence or presence of metformin

From: Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced rats

Groups

Without metformin

With metformin

 

Control

Sham

PCOS

Total

Control

Sham

PCOS

Total

Total

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

Expansion

25 (40.32)

25 (40.98)

22 (32.83)

72 (37.98)

34 (53.96)

35 (57.37)

35 (53.03)a)

104 (54.73)a)

176 (46.31)

Semi expansion

16 (25.80)

17(27.86)

17 (25.37)

50 (26.31)

22 (34.92)

23 (37.70)

20 (30.30)

65 (34.21)a)

115 (30.26)

No expansion

19 (30.65)

15 (24.59)

23 (34.32)

57 (30.00)

7 (11.11)

2 (3.27)

10 (15.15)a)

19 (10.00)a)

76 (20.00)

Degeneration

2 (3.23)

4 (6.55)

5 (7.46)

11 (5.78)

0 (00.00)

1 (1.63)

1 (1.51)a)

2 (1.05)a)

13 (3.43)

Total

62

61

67

190

63

61

66

190

380

  1. PCOS polycystic ovary syndrome
  2. a)Significant differences from the absence of metformin (p < 0.05)