Skip to main content

Table 3 Nuclear maturation of rat oocytes in control, sham, and PCOS groups in the absence and presence of metformin

From: Does metformin improve in vitro maturation and ultrastructure of oocytes retrieved from estradiol valerate polycystic ovary syndrome-induced rats

Groups

Without metformin

With metformin

 

Control

Sham

PCOS

Total

Control

Sham

PCOS

Total

Total

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

GV

4 (13.79)

3 (10.34)

4 (14.28)

11 (12.79)

3 (10.34)

4 (13.79)

3 (10.71)

10 (11.62)

21 (12.20)

GVBD

6 (20.68)

5 (17.24)

5 (17.85)

16 (18.60)

6 (20.68)

6 (20.68)

6 (21.42)a

18 (20.93)

34 (19.76)

MI

6 (20.68)

6 (20.68)

5 (17.85)

17 (19.76)

7 (24.13)

7 (24.13)

6 (21.42) a

20 (23.25)

37 (21.51)

A-T

1 (3.44)

3 (10.34)

2 (7.14)

6 (6.97)

1 (3.44)

1 (3.44)

2 (7.14)

4 (4.65)

10 (5.81)

MII

5 (17.24)

5 (17.24)

4 (14.28)

14 (16.27)

5 (17.24)

5 (17.24)

4 (14.28)

14 (16.27)

28 (16.27)

Deg

2 (6.89)

2 (6.89)

3 (10.71)

7 (8.13)

2 (6.89)

1 (3.44)

3 (10.71)

6 (6.97)

13 (7.55)

ND

5 (17.24)

5 (17.24)

5 (17.85

15 (17.44)

5 (17.24)

5 (17.24)

4 (14.28)

14 (16.27)

29 (16.86)

Total

29

29

28

86

29

29

28

86

172

  1. PCOS polycystic ovary syndrome; GV germinal vesicle; GVBD germinal vesicle breakdown; MI metaphase I; A-T anaphase-telophase; MII metaphase II; Deg. degenerated; ND not-detectable
  2. a)Significant differences from without metformin, (p < 0.05)