Fig. 4

Bioinformatics and luciferase reporter assay results. a The 3’-untranslated region (3’-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. b MiR-186 significantly decreased the relative luciferase activity of the wild-type ABCC1 3’UTR compared with the mutant ABCC1 3’UTR. Results are representative of three separate experiments. Data are expressed as the mean ± standard deviation. * P < 0.05