Fig. 4

RNAseq analysis of FVB MOE secretory cells treated with E2 and 4OHT. a Venn diagram of overlap of regulated genes between conditions. b-d qPCR analysis of genes identified as E2 regulated by RNAseq. Significant difference from DMSO control represented by *** (p < 0.001) and * (p < 0.05) for b) Csf2. c) Dhrs9. d) Dcn. e Heat map of genes significantly regulated by E2 clustered by GO analysis for biological processes. Log2 Fold change shown for DMSO versus E2 and DMSO versus 4OHT