Fig. 3

FasAb -induced apoptosis in cultured KGN cells, quantified by caspase 3/7 activity (RLU ± SEM) following inhibition of de novo protein synthesis. The cultures were exposed to cycloheximide (0.25 μg/mL; CHX), for a total of 10 h and FasAb (1 μg/mL) during the last 8 h of culture. Staurosporine treatment (1 μM) was included as the positive experimental control (n = 6 independent experiments; different letters denote differences, P < 0.05)