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Table 4 Evaluation of selected characteristics among patients depending on the diagnosis of breast cancer before prophylactic surgery

From: Prophylactic salpingo-oophorectomy in BRCA1 mutation carriers and postoperative incidence of peritoneal and breast cancers

Characteristic

Breast cancer before surgery

Not identified n = 115

 

Identified n = 80

 

N

p

Death

1

0.87 %

12

15.00 %

13

p = 0.00010

Development of cancer

6

5.22 %

10

12.50 %

16

p = 0.06835

Development of peritoneal cancer

0

0.00 %

2

2.50 %

2

p = 0.08832

Development of breast cancer

6

5.22 %

8

10.00 %

14

p = 0.20318

Development of primary breast cancer

6

5.22 %

3

3.75 %

9

p = 0.63096

 

5382insC

78

67.83 %

50

62.50 %

128

p = 0.44111

Type of mutation

C61G

24

20.87 %

24

30.00 %

48

p = 0.14543

 

4153DelA

13

11.30 %

6

7.50 %

19

p = 0.37823