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Fig. 6 | Journal of Ovarian Research

Fig. 6

From: Small putative NANOG, SOX2, and SSEA-4-positive stem cells resembling very small embryonic-like stem cells in sections of ovarian tissue in patients with ovarian cancer

Fig. 6

Tumor-like structures (arrows) developed in “chambers” present in ovarian tissue (a-g). They were present in ovaries of women with borderline ovarian cancer and high-grade serous ovarian carcinoma. The tumor-like structures were strongly NANOG-positive (c-g). A small proportion of tumor-like structures in borderline ovarian cancer was mineralized and with no visible nuclei (b). Some tumor-like structures were composed of small cells with clearly visible nuclei (g). (Light microscope: a-d, g, magnification 100x and 1000x; inverted microscope: e-f, magnification 200x). Legend: brown-NANOG-positivity, blue-nuclei after HE staining. Red Bars: 100 μm for a-d, g and 10 μm for e, f

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Journal of Ovarian Research

ISSN: 1757-2215

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