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Table 1 Biomarkers with high potential for early screening and diagnosis of OVC

From: The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer

Gene list

ATP7B

CA125

CLEC3B

KLK6

TOP2A

ARID4B

CEA

ID2

IGFBP2

INHA

PDGFA

HE4

DUSP1

BSG

CLDN3

REEP5

MIF

IGF2BP1

LGALS3BP

CDC25C

BRCA2

CA72-4

IL13RA2

STAT3

CLDN4

CCT3

AFP

IQGAP1

MSLN

NME1

DNAJC15

BARD 1

PLK1

RAET1E

COPS5

CD47

PRL

RHOC

ST14

AKT2

KLK14

BCL2

VIL2

TITF1

CSF1

ETV4

MUC 1

RNASE2

AMH

ANGPT2

KLK9

IGFII

APOD

TFF1

EFNB1

MAGEA4

AMH

SYCP1

CDC25A

XIST

WFDC2

BAG1

CD247

SPINK1

KLK11

SCGB2A1

WT 1

TRIM25

CSF1R

KLK10

ERCC1

BAG3

CDC25B

PRSS8

KLK13

SIX5

OGP

P11

GADD45A

KLK15

KLK8

BAG 4

DAB2

CCNE1

MVP

ZNF217

CDX2

CYP2A

HLA-G

KLK5

RBL2

OPN

HMGA1

CEACAM6

PARP1

EYA2

SMRP

PTK2

JUP

KLK7

SKP2

Maspin

HOXB7

ETS1

VEGFC

ELF1

Bcl-xL

TACC3

MLANA

SOD2

IGFBP5

MSN

BCHE

EPHA2

ASNS

MUC5AC

TNFRSF1B

   
  1. Genes that were differentially regulated in OVC were identified by mining the Cancer Gene Index (CGI) by BioXM software. The search identified 117 differentially regulated genes. Of these, 13 genes were identified that exhibited major differential expression in 19 OVC cell lines vs. normal ovarian cell lines (P < 0.05 in all comparisons) (underlined and bold type)
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Journal of Ovarian Research

ISSN: 1757-2215

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