Fig. 6
From: HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells
HE4 promotes tubulin deregulation in SKOV3 and OVCAR8 cells. a Quantitative RT-PCR of MAPT in SKOV3-NV and SKOV3-C1 cells, normalized to 18 s rRNA. **p < .05 b SKOV3-WT and OVCAR8-WT cells were left untreated or treated with 20 nM recombinant HE4, and protein was collected at the indicated timepoints. Levels of β-tubulin and α-tubulin were determined by western blot, with GAPDH used as a loading control. c-d Densitometry analysis of β-tubulin and α-tubulin, normalized to GAPDH, from western blot in (b)