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Table 1 Factors associated with pre-surgical adverse DOR in patients scheduled for laparoscopic cystectomy for endometriomas

From: Evaluation of factors predicting diminished ovarian reserve before and after laparoscopic cystectomy for ovarian endometriomas: a prospective cohort study

Characteristics

Univariate analysis

Multivariate analysis

Adverse DOR (n = 31)

Non-DOR (n = 112)

P value

OR (95%CI)

P value

Patient characteristics

 Age (years)

37.9 ± 4.1 (36.4–39.4)

33.5 ± 4.9 (32.6–34.4)

<0.001

1.26 (1.11–1.43)

<0.001

 Gravidity (%)

0.5 ± 0.8 (0.2–0.7)

0.2 ± 0.5 (0.1–0.2)

0.02

 Parity (%)

0.4 ± 0.6 (0.1–0.6)

0.1 ± 0.4 (0.03–0.2)

0.02

 Body mass index (kg/m2)

22.0 ± 6.5 (19.6–24.4)

21.4 ± 5.0 (20.5–22.4)

0.64

  

Laterality of cysts

 Unilateral (%)

10 (32.3)

64 (57.1)

0.01

 Bilateral (%)

21 (67.7)

48 (42.9)

 Total size of ovarian cyst (mm)

83.1 ± 32.2 (71.3–94.9)

73.1 ± 27.5 (67.9–78.2)

0.09

  

Pre-surgical serum hormone concentrations

 LH (mIU/mL)

9.7 ± 9.9 (6.1–13.4)

6.2 ± 8.4 (4.6–7.8)

0.047

 FSH (mIU/mL)

10.3 ± 7.0 (7.7–12.8)

6.5 ± 3.5 (5.8–7.1)

<0.001

1.16 (1.05–1.28)

0.003

 Estradiol (pg/mL)

134.5 ± 167.1 (73.2–195.8)

72.3 ± 87.2 (56.0–88.6)

0.01

 CA125 (U/mL)

90.1 ± 104.7 (51.7–128.5)

68.9 ± 53.0 (58.9–78.8)

0.12

  
  1. Abbreviations: CA125 cancer antigen 125, CI confidence interval, DOR diminished ovarian reserve, FSH follicle-stimulating hormone, LH luteinising hormone, OR odds ratio
  2. Data are expressed as mean ± standard deviation (95 % CI) or number (percentage) of patients