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Table 1 Factors associated with pre-surgical adverse DOR in patients scheduled for laparoscopic cystectomy for endometriomas

From: Evaluation of factors predicting diminished ovarian reserve before and after laparoscopic cystectomy for ovarian endometriomas: a prospective cohort study

Characteristics Univariate analysis Multivariate analysis
Adverse DOR (n = 31) Non-DOR (n = 112) P value OR (95%CI) P value
Patient characteristics
 Age (years) 37.9 ± 4.1 (36.4–39.4) 33.5 ± 4.9 (32.6–34.4) <0.001 1.26 (1.11–1.43) <0.001
 Gravidity (%) 0.5 ± 0.8 (0.2–0.7) 0.2 ± 0.5 (0.1–0.2) 0.02
 Parity (%) 0.4 ± 0.6 (0.1–0.6) 0.1 ± 0.4 (0.03–0.2) 0.02
 Body mass index (kg/m2) 22.0 ± 6.5 (19.6–24.4) 21.4 ± 5.0 (20.5–22.4) 0.64   
Laterality of cysts
 Unilateral (%) 10 (32.3) 64 (57.1) 0.01
 Bilateral (%) 21 (67.7) 48 (42.9)
 Total size of ovarian cyst (mm) 83.1 ± 32.2 (71.3–94.9) 73.1 ± 27.5 (67.9–78.2) 0.09   
Pre-surgical serum hormone concentrations
 LH (mIU/mL) 9.7 ± 9.9 (6.1–13.4) 6.2 ± 8.4 (4.6–7.8) 0.047
 FSH (mIU/mL) 10.3 ± 7.0 (7.7–12.8) 6.5 ± 3.5 (5.8–7.1) <0.001 1.16 (1.05–1.28) 0.003
 Estradiol (pg/mL) 134.5 ± 167.1 (73.2–195.8) 72.3 ± 87.2 (56.0–88.6) 0.01
 CA125 (U/mL) 90.1 ± 104.7 (51.7–128.5) 68.9 ± 53.0 (58.9–78.8) 0.12   
  1. Abbreviations: CA125 cancer antigen 125, CI confidence interval, DOR diminished ovarian reserve, FSH follicle-stimulating hormone, LH luteinising hormone, OR odds ratio
  2. Data are expressed as mean ± standard deviation (95 % CI) or number (percentage) of patients