Skip to main content

Table 3 Factors associated with post-surgical adverse DOR at 3 months after laparoscopic cystectomy

From: Evaluation of factors predicting diminished ovarian reserve before and after laparoscopic cystectomy for ovarian endometriomas: a prospective cohort study

 

Univariate analysis

Multivariate analysis

Adverse DOR (n = 38)

Non-adverse DOR (n = 74)

P value

OR (95 % CI)

P value

Patient characteristics

 Age (years)

34.9 ± 5.0 (33.2–36.5)

32.8 ± 4.8 (31.7–33.9)

0.04

 Gravidity (%)

0.2 ± 0.6 (0.01–0.4)

0.1 ± 0.9 (0.04–0.2)

0.67

  

 Parity (%)

0.2 ± 0.5 (0.2–0.3)

0.1 ± 0.3 (0.01–0.2)

0.47

  

 Body mass index (kg/m2)

21.8 ± 4.6 (20.2–23.3)

21.3 ± 5.2 (20.1–22.5)

0.67

  

Laterality of cysts

 Unilateral (%)

13 (34.2)

51 (68.9)

<0.001

4.7 (1.93–11.5)

0.001

 Bilateral (%)

25 (65.8)

23 (31.1)

   

 Total size of ovarian cyst (mm)

79.9 ± 35.0 (68.4–91.4)

69.6 ± 22.2 (64.4–74.7)

0.06

  

Pre-surgical serum hormone concentrations

 LH (mIU/mL)

4.5 ± 4.0 (3.2–5.8)

7.0 ± 10.0 (4.7–9.3)

0.13

  

 FSH (mIU/mL)

6.4 ± 2.6 (5.6–7.3)

6.5 ± 3.9 (5.6–7.4)

0.96

  

 Estradiol (pg/mL)

79.4 ± 93.3 (48.7–110.1)

68.7 ± 84.3 (49.1–88.2)

0.54

  

 CA125 (U/mL)

65.5 ± 44.2 (50.9–80.0)

70.6 ± 57.1 (57.4–83.9)

0.63

  

 AMH (ng/mL)

2.8 ± 1.7 (2.2–3.4)

4.6 ± 3.1 (3.9–5.3)

0.001

0.65 (0.48–0.88)

0.005

Peri-surgical findings

 Re-ASRM score

60.9 ± 32.1 (50.4–71.4)

49.4 ± 27.5 (43.0–55.7)

0.05

  

 Total surgical duration (min)

91.5 ± 40.8 (78.1–104.9)

81.9 ± 32.0 (74.5–89.3)

0.18

  

 Total blood loss (mL)

40.2 ± 46.1 (25.0–55.3)

23.9 ± 26.8 (17.7–30.1)

0.02

  1. Abbreviations: AMH anti-Müllerian hormone, CA125 cancer antigen 125, CI confidence interval, DOR diminished ovarian reserve, FSH follicle-stimulating hormone, LH luteinising hormone, OR odds ratio, Re-ASRM revised American Society of Reproductive Medicine
  2. Data are expressed as mean ± standard deviation (95 % CI) or number (percentage) of patients