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Table 1 Chemosensitivity using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay

From: Establishment and characterization of a cell line (HCH-1) originating from a human clear cell carcinoma of the ovary

Drug

EC50

PPC

 

(μg/mL)

(μg/mL)

ACD

0.008

0.08

ADM

0.62

0.4

BLM

184.4

3.3

CBDCA

27.0

37.1

CDDP

3.9

8.5

CPA

6.9

4.3

CPT-11

0.511

0.05

5-FU

61.5

15.3

MMC

1.4

2.4

MTX

>300

3

PTX

68.6

11.8

VCR

61.7

0.1

VLB

18.6

0.15

VP-16

52.4

13

  1. EC50, effective concentration for 50 % kill; PPC, peak plasma concentration taken intravenously; ACD actinomycin D, ADM doxorubicin, BLM bleomycin, CBDCA carboplatin, CDDP cisplatin, CPA 4-hydroperoxy-cyclophosphamide, CPT-11 irinotecan hydrochloride, 5-FU 5-fluorouracil, MMC mitomycin C, MTX methotrexate, PTX paclitaxel, VCR vincristine, VLB vinblastine, VP-16 etoposide
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Journal of Ovarian Research

ISSN: 1757-2215

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