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Table 1 Chemosensitivity using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay

From: Establishment and characterization of a cell line (HCH-1) originating from a human clear cell carcinoma of the ovary

Drug EC50 PPC
  (μg/mL) (μg/mL)
ACD 0.008 0.08
ADM 0.62 0.4
BLM 184.4 3.3
CBDCA 27.0 37.1
CDDP 3.9 8.5
CPA 6.9 4.3
CPT-11 0.511 0.05
5-FU 61.5 15.3
MMC 1.4 2.4
MTX >300 3
PTX 68.6 11.8
VCR 61.7 0.1
VLB 18.6 0.15
VP-16 52.4 13
  1. EC50, effective concentration for 50 % kill; PPC, peak plasma concentration taken intravenously; ACD actinomycin D, ADM doxorubicin, BLM bleomycin, CBDCA carboplatin, CDDP cisplatin, CPA 4-hydroperoxy-cyclophosphamide, CPT-11 irinotecan hydrochloride, 5-FU 5-fluorouracil, MMC mitomycin C, MTX methotrexate, PTX paclitaxel, VCR vincristine, VLB vinblastine, VP-16 etoposide