Fig. 4From: UHRF1 gene silencing inhibits cell proliferation and promotes cell apoptosis in human cervical squamous cell carcinoma CaSki cellsCell cycle detected by flow cytometer. Compared with the Blank group and the NC group, the ratio of S-G2M phase cells in UHRF1 Silence group decreased significantly, while the ratio of G0/G1 phase cells increased obviously. The UHRF1 Silence group induced the apoptosis of CaSki cells, which could be substantiated by the appearance of sub-G1 peak in flow cytometric DNA histogram. The peak appeared ahead of the G0/G1 peak, and represented cell apoptosis. *, P < 0.05 compared with the Blank group; #, P < 0.05 compared with the NC group; n = 3; UHRF1, ubiquitin-like, containing plant homeodomain (PHD) and really interesting new gene (RING) finger domains 1; NC, negative controlBack to article page